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Transonic 400 Series Flowmeters

Above: T403 Triple Channel Console
Holds up to three perivascular or tubing flowmeter modules.
The T403 console may be populated with one module or two
modules (as shown) with blanks for expansion, or be
filled to capacity with three modules.
Dimensions 5.21 " high x 13.46" wide x 12" deep

Introducing the NEW T400 Series Modular Flowmeters from Transonic

Innovative transit-time flow technology in space-conserving modules mix and match in 2 or 3-channel plug-in consoles. The consoles are durable, streamlined cases with a shared power supply for plug-in flowmeter modules. It is also a backplane signal processor for outputting analog signal block connections.

400-Series Consoles are available in two sizes: T402 - with capacity for two modules or T403 - with capacity for three modules.

Note: Transonic T106 and T206 Flowmeters are being phased out by July 2002. Support, including the supply of probes, cables, connectors and repairs will continue for the time being.

New Modules

TS420 Perivascular Flowmeter Module

Transonic Systems' hallmark simple plug & play mode of operation

Accepts M-PS-Series acute/chronic perivascular probes with precision offset and resolution specifications

Operates M-PAX 4-crystal cardiac output probes with independent crystal pairs for improved acoustic monitoring

Accurately measures volume flow of less than 1 ml/min

Expanded ultrasonic frequency range for the smallest flowprobes imaginable! Implantable 0.5 mm and 0.7 mm nanoprobes!

160 Hz bandwidth to accurately characterize flow dynamics at high heart rates

Analog meter displays voltage proportional to flow

Easy access front panel receptable for chronic probe calibration keys

TS420 Perivascular Flowmeter
The next generation to gold
standard T106/T206 flowmeters

TS410 Tubing Flowmeter

Lowest signal-to-tubing ratio ever for tubing flow measurement

Operates ME-PXL-Series 4-transducer sterile tubing flowsensors:precision specifications

Operates ME-PXN-Series 4-crystal inline flowprobes (available soon): precision specifications

Programmable gain for user calibration with different fluid/temperatures

Programmable alarms: low/high flow; received signal threshold alarm

Easy-to-read numeric LED displays set-up/system status

Applications: isolated perfused organ flow measurement, fluid dynamics, mock circulatory models, pump and VAD device testing, bioreactor studies with cell culture media

TS410 Tubing Flowmeter and
sterile tubing flowsensor
A dedicated module for flow
measurement in tubing

Preconfigured Combinations
Catalog numbers for preconfigured consoles use the following suffix designations for modules:

(-T)   TS410 Tubing Flowmeter
(-P)   TS420 Perivascular Flowmeter
(-B)   blank expansion slot

Single-Channel Combinations

TS402-PB    2-channel console with one TS420
TS403-PBB   3-channel console with one TS420
TS402-TB    2-channel console with one TS410
TS403-TBB   3-channel console with one TS420

Dual-Channel Combinations

TS402-PP    2-channel console with two TS420
TS403-PPB   3-channel console with two TS420
TS402-TT    2-channel console with two TS410
TS403-TTB   3-channel console with two TS420
TS402-PT    2-channel console with one TS420
                     and one TS410
TS403-PTB   3-channel console with one TS420
                     and one TS410

Triple-Channel Combinations

TS403-PPP   3-channel console with three TS420
TS403-PPB   3-channel console with two TS420
                      & one TS410
TS402-PTT    3-channel console with one TS410
                      & two TS410
TS403-TTT   3-channel console with three TS410

T402 -PP: dual channel flowmeter
console with two TS420 Perivascular Flowmeter modules.

NEW Nanoprobes!

Above:
Comparison: 0.5 mm (0.5PSB) Nanoprobe (left) compared to standard 0.5 mm V probe (right) and the tip of a ball-point pen (top).

1.5PSL probe for ascending aorta.

Unprecedented Capability

Continuous real-time volume flow measurements in ml/min in conscious and anesthetized models for calculation of cardiac output, stroke volume and vascular resistance.

The Smallest Flowprobes Imaginable!

Transonic 0.5PSB and 0.7PSB Precision Flowprobes use nanofabrication techniques to photo-etch structures scaled to fit murine anatomy.

Gold Standard Accuracy

Validated ultrasonic transit-time technology: Waveforms demonstrate Transonic's signature zero baseline stability and high resolution of flows less than 1 ml/min..

Nanoprobe on murine renal artery (left) and waveform of conscious
renal blood flow day 1 after implant of 0.7SB flowprobe (above).
Courtesy of M. Callahan, Wake Forest University Medical College

Specifications and Accessories for Murine Applications

Size

VESSEL
MC-probe

VESSEL
MA-probe

BI-DIRECTIONAL FLOW

ACCURACY

ULTRA-
SOUND

Probe

mm

OD mm
chronic

OD mm
acute

Resol- Scale Maximum
ution1 Settings2 Range3

Low Flow Normal Flow
ml/min ml/min ml/min ml/min

Zero Ab. Relative
Offset4 Acc.5 Acc.

ml/min % %

Frequency

MHz

PS-Series Nanoprobes

0.5PS
0.7PS
1.5PS

1PR

0.3-0.48
0.4-0.7
1.2-1.5

0.7 - 1.0

0.3-0.5
0.5-0.7
1.2-1.5

0.7 - 1.2

   0.03        1.5        6           30
   0.05         2.5      10           50
   0.075      10.0      40          200

0.05 5 20 100

�0.12      � 15      � 2
�0.2        � 15      � 2
�0.8        � 15      � 2

�0.8 � 10 � 2

14.4
9.6
4.8

7.2

Nanoprobe

Physical

Specifications

Probe

Cable Orientation

Width

Length

Depth

Lumen

Maximum Cable Length

0.5PS
0.7PS
1.5PS

1PR

back or side
back or side
lateral only

back or side

3.2 mm
3.2 mm
4.25 mm

6.5 mm

3.3 mm
3.5 mm
3.75 mm

5.5 mm

1.0 mm
1.2 mm
2.0 mm

4.0.5 mm

0.470 mm
0.65 mm
1.650 mm

1.1 x 1.5 mm

30 cm
30 cm
30 cm

60 cm