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BN-NICO - BioNomadix Cardiac Output Pair

BIOPAC BN-NICO / BN-NICO-T - BioNomadix Cardiac Output

The NICO BioNomadix amplifier is designed to record high resolution cardiac impedance waveform data (Impedance Magnitude (Z) and Derivative of Impedance (dZ/dt)). The transmitter unit can be used either with an MP160/MP150 using a matched receiver unit, or directly with a BioNomadix Logger. The matched pair emulates a "wired" connection from subject to computer, with all the benefits of a fully-wireless recording system.
Code
BN-NICO

BIOPAC BN-NICO / BN-NICO-T - BioNomadix Cardiac Output

BIOPAC BN-NICO BioNomadix Cardiac Output Wireless Transmitter & Receiver Pair (for use with MP160/MP150 or BioNomadix Logger)

BIOPAC BN-ECG2-T - BioNomadix Cardiac Output Amplifier/Transmitter module only (BioNomadix Logger use only)

The NICO BioNomadix amplifier is designed to record high resolution cardiac impedance waveform data (Impedance Magnitude (Z) and Derivative of Impedance (dZ/dt)). The transmitter unit can be used either with an MP160/MP150 using a matched receiver unit, or directly with a BioNomadix Logger. The matched pair emulates a "wired" connection from subject to computer, with all the benefits of a fully-wireless recording system.

The unit is specifically designed to measure impedance magnitude and derivative of impedance, for the purposes of beat-by-beat impedance, stroke volume and cardiac output measurements. The module pair establishes a maximum bandwidth of DC to 10 Hz for both the Z and dZ/dt signals. Additional internal lowpass optional filters provide for improved amplification of Z and dZ/dt signals, depending upon ambient conditions.

The BN-NICO is typically used to measure cardiac-related impedance changes in the body via a tetrapolar electrode configuration. Generally stated, at least two "outside" electrodes are used to source a constant AC current (1 ma rms at 50 kHz) and at least two "inside" electrodes are used to measure the voltage across the impedance under investigation. Because the current is constant, the measured voltage is directly proportional to measured impedance.

A variety of tetrapolar electrode arrangements can be accommodated with the module pair. Multiple electrodes can be used to source/sink the applied constant current to reduce current density at any one electrode site.
Equipotential (strip) electrodes can be used on the voltage sense electrodes to establish a clear measurement line for determining electrode distances for use in stroke volume estimating formulas (such as Kubicek, Sramek or Sramek-Bernstein). Use AcqKnowledge's impedance cardiography analysis tools to perform dZ/dt classification, motion artifact removal, Pre-ejection period (PEP) estimation and a variety of related indexes and ratios. Click for ICG Analysis video...

Raw data from the device is bandlimited from DC to 10 Hz, to provide for a sufficiently rapid response impedance measurement, without compromising the impedance signal with corrupting EMG or other artifact.
Due to battery operation of the wireless transmitter and close proximity to the subject's body, common-mode rejection ratio is extremely high, considerably in excess of any typical wired biophysical signal recording system.

The high signal to noise ratio and high time-based sampling resolution permits the BN-NICO to be used for precise cardiac impedance, stroke volume and cardiac output research studies. Impedance measurement can also be synchronized to specific stimuli for a variety of stimulus/response investigations, such as those associated with Challenge and Threat.

Attach the transmitter near, or on, the subject's torso via stretchy Velcro strap (included) or try the stretch-mesh, pocketed BioNomadix Shirt. Interference with other recording modules or systems is greatly minimized because the module transmitter is completely battery operated and Operates totally independently of any other recording grounds or power sources. The recording transmitter is also extremely safe to use, because there is no physical connection to supply mains.

The BioNomadix Cardiac Output (NICO) Pair consists of two parts, a transmitter with strap that is worn by the subject to amplify and send the physiological data, and a receiver module to provide high-quality cardiac output data (Z and dZ/dt). The BioNomadix NICO transmitter uses digital transmission and short leads placed close to the signal source to provide excellent signal quality. BioNomadix are configured for specific signal types, so you don’t have to adjust settings on the hardware or software for high quality cardiac output data.

The transmitter's battery can provide power for up to 72 hours of continuous operation.

The BioNomadix series of wireless, wearable physiology monitoring devices for life science research are available for a wide range of signals, including ECG, EEG, EOG, EMG, EGG, Respiration, Pulse, Temperature, Electrodermal Activity, Impedance Cardiography and Accelerometry. BioNomadix are typically dual-channel units, offering either two of the same signal or a combination of signals.

BioNomadix noninvasively records high-quality, full-bandwidth data while comfortably allowing subjects to move freely in natural indoor environments. Each BioNomadix device consists of two parts, a transmitter that is worn by the subject to amplify and send the physiological data, and a receiver module or BioNomadix Logger. BioNomadix transmitters use digital transmission and short leads or transducers placed close to the signal source to provide excellent signal quality. BioNomadix are configured for specific signal types, so you don’t have to adjust settings on the hardware or software for high quality data.

Multiple BioNomadix units can be used to provide the optimum signal combination for a research study requiring biopotential or transducer signals. When used with a BIOPAC MP System, up to 16 channels of BioNomadix data can be recorded for multi-subject or multi-parameter protocols. The system also works with multiple MP160/MP150 systems or third-party data acquisition hardware via an isolated power supply module (IPS100C). The BioNomadix Logger can pair with up to 3 transmitter units providing up to 6 channels of physiological data as well as a color display for visual feedback, speaker for auditory feedback, vibration for haptic feedback, voice journal for participant comments, event markers, alarms, and a built-in accelerometer.  AcqKnowledge software adds the power of sophisticated automation and scoring routines for each signal type, plus customization options.

BioNomadix accessory items include transducers, electrode leads, and a custom, pocketed stretch-mesh shirt to comfortably hold multiple devices in place. The shirt has zippers placed for easy access to electrode sites and is available from extra small to extra large.

Developed and manufactured by BIOPAC Systems Inc., a leader in life science data acquisition and analysis, the new BioNomadix series delivers all the benefits of a wireless solution with the signal quality & integrity of a wired system. BioNomadix provides a cost-efficient option for uncompromised wireless physiological subject monitoring.

BioNomadix Transmitter and Receiver are shipped as a pair with matching serial numbers and include a strap and battery charger. To identify the matched Transmitter-Receiver Pair, press and hold "ID" button on Transmitter and match to Receiver with flashing "Status" LED.

Applications

Impedance Cardiography (ICG) / Cardiac Output

BioNomadix Transmitter and Receiver are shipped as a pair with matching serial numbers and include a strap and battery charger. To identify the matched Transmitter-Receiver Pair, press and hold "ID" button on Transmitter and match to Receiver with flashing "Status" LED.

Wireless NICO Specifications

Signal type: Noninvasive Cardiac Output - CH A - Impedance Magnitude (Z) and
                 CH B - Derivative of Impedance (dZ/dt)

Bandlimits: Max: DC to 10 Hz; Factory preset: DC to 10 Hz
               Filter Options: DC, 1 Hz LP, 10 Hz LP

Noise (resolution):  Z ~0.05 ohms (rms) at 10 Hz bandwidth
                          dZ/dt ~0.0075 ohms/sec (rms) at 10 Hz bandwidth

Input Voltage Range: Z 1 to 100 ohm (mag); dZ/dt ±10 ohm/sec

Output Voltage Range: ±10 V (receiver output)

Data transmit rate: 2,000 Hz (between BioNomadix transmitter and receiver)

Operating time: ~24 hours continuous operation from full-charge

Transmitter: ultra-low power, 2.4 GHz bi-directional digital RF transmitter

Transmitter LED: Charge when YELLOW (blinking rate changes based on operational mode); unit has approx. 1 hour of power remaining when LED blinks all turn YELLOW.

Transmitter Battery: L-ion battery: full charge ~1 hour, ~500 charge cycles

Charger: BN-CHARGER battery charger included with each module pair

Receiver Power: MP160/MP150 Research System, isolated power supply IPS100C or BioNomadix Logger

Included strap: 137 cm - BN-STRAP137; additional sizes available

Size & Weight: Transmitter (approx.): 6 cm x 4 cm x 2 cm; 54 grams
                     Receiver (approx): 4 cm x 11 cm x 19 cm; 380 grams

Input (signal source): Z BN-EL50-LEAD4 recommended (BN-ELxx-LEAD2 alternative); dZ/dt BN-EL50-LEAD4 recommended (BN-ELxx-LEAD2 alternative)

Advanced Setup Options
For details on these advanced options, see the MP Hardware Guide (available under the AcqKnowledge Help menu or Support > Manuals).

Calibration

Calibration is not required—BioNomadix are factory-calibrated for specific signal types. For optional calibration to validate measurements, see the MP Hardware Guide.

Filter options

Switches can be set to enable the mains 50/60 Hz notch filter and to set optional impedance (Zo) signal bandwidths (DC, 1 Hz LP, 3 Hz LP, 5 Hz LP, 10 Hz LP).