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XenoWorks™ Digital Microinjector

Designed primarily for transgenic mammal workstations, the XenoWorks Digital Microinjector is capable of holding oocytes and early embryos immobile while simultaneously providing a separate pressure channel for pronuclear microinjection of DNA or the gentle control of embryonic stem cells as they are transferred into blastocysts.
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XenoWorks™ Digital M

XenoWorks™ Digital Microinjector

Designed primarily for transgenic mammal workstations, the XenoWorks Digital Microinjector is capable of holding oocytes and early embryos immobile while simultaneously providing a separate pressure channel for pronuclear microinjection of DNA or the gentle control of embryonic stem cells as they are transferred into blastocysts.

The microinjector employs two independent pressure control channels. The self-contained vacuum channel for gentle suspension-cell holding applications can be switched on and off as needed, and a responsive rotary control is used to dial the pressure up or down according to the degree of hold required.

A second channel is available which is capable of delivering both high-pressure for solution injection, and gentle positive/negative pressure for transfer of embryonic stem cells. Two modes of injection are available on this channel; in Constant Flow mode, the inject pressure set is applied to the micropipette tip for as long as the hand- or foot-switch is held down. In Pulse mode, the inject pressure is applied for a precisely timed duration, which can be set in 0.1 second increments. Both injection duration and pressure are easily selectable using rotary controls on the remote interface. Optimal ergonomics are again a prime consideration; the remote control unit provides access to all keys and rotary controls necessary to manipulate the parameters in the two pressure channels, while the separate compressor module can be shelf- or floor-mounted away from the microscope to eliminate vibration interference.


Digital Microinjector Features

Built-in compressor with remote user interface
Two independent pressure channels
Negative and positive pressure
Two injection modes: pulse and continuous
Four functions: Hold, Transfer, Inject, Clear
Transfer channel provides compensation pressure for high pressure injection
Four range settings for transfer/compensation pressure
Rotary controls for continuous pressure adjustment


Specifications

 

Digital Microinjector Specifications  
Hold Function  
Hold Pressure: -350 to +350 hPa in 1hPa increments
   
Inject Functions  
Inject Modes: Continuous or pulse
   
Inject Presure: 0 to 5600 hPa in 7hPa increments
Inject Time: 0 to 10 seconds in 0.1 second increments
Compensation Pressure: adjustable in 1hPa increments
Clear Pressure: Ramps from current Inject value to 5600 at 1000 hPa/sec.
Inject Command: Remote interface or foot switch
   
Transfer Function  
Transfer Pressure: -175 to +175 hPa in 1hPa increments
Maximum Pressure 5600 hPa (inject channel)
Controls Tactile keys, rotary optical encoders 3 x 7-segment LED display
   
Micropipette Holder  
Diameter: 4mm
Accepts 1mm O.D. capillary glass
2m ETFE tubing included  
   
Electrical  
BRE220: 220-240 Volts, 50Hertz
   
Dimensions  
Size:  
Compressor module 407mm x 440mm x 150mm,
User interface module 164mm x 123mm x 70mm
   
Weight:  
Compressor module: 1504g
User interface module: 42g

Ordering Information

 

XenoWorks Digital Microinjector  
BRE220 XenoWorks Digital Microinjector (220V) Includes: compressor module, footswitch, remote user interface, 2 micropipette holders with 2.4m ETFE tubing and fittings, spare tubing, connecting cables, and manual
   
Xenoworks Accessories  
BR-DT XenoWorks Digital Tubing Kit
BR-MH XenoWorks Micropipette Holder