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38500 - P.A.M. Pressure Application Measurement

The P.A.M. (Pressure Application Measurement) device is a novel tool for measuring mechanical pain threshold.
Code
38500

38500 - P.A.M. Pressure Application Measurement

“PAM device standard package (PN 38500), shown with pedal
switch, small and large joint transducer and Usb cable”.

The P.A.M. (Pressure Application Measurement) device is a novel tool for measuring mechanical pain threshold. It was specifically designed for Arthritis research and is therefore especially suited to assess joint hypersensitivity in rodents knees or ankles. The PAM device can also be used to measure mechanical sensitivity in mice and rats paw, by using a specific Paw Pressure Transducer (optional).

The PAM device has been designed and validated specifically for the mechanical stimulation and assessment of joint pain, as it applies a quantifiable force for direct stimulation of the joint and for automatic readout of the response.
 
The operator simply wears a special force sensor on his or her thumb and the peak amplifier measures the force which elicits the animal response (normally, limb withdrawal).
 
Each PAM device comes standard with two force sensors, which have been specially designed to apply force to rat and mouse joints.
 
N. J. Barton et al. 2007 Pressure application measurement (PAM): “A novel behavioural technique for measuring hypersensitivity in a rat model of joint pain”. Journal of Neuroscience Methods 163, 67–75.